Barely Significant
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Long-term oral anticoagulation for atrial fibrillation in low and middle income countries.

Indian Heart J · 2021 · PMC8065364 · PMID 33865530

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a decreasing trendno p-value reported
Due to a decreasing trend in the prevalence of rheumatic heart disease (RHD), valve disease as a primary cause of AF now constitutes a small fraction of all people with AF.

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