According to data from the literature, the solubility of Curcumin in water is very low, almost insignificant [ 44 ]; the solubility of Curcumin in oil increases slightly [ 45 ], but in microemulsion and gel microemulsion systems, it is possible to solubilize a significant amount of Curcumin.
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Novel Gel Microemulsion as Topical Drug Delivery System for Curcumin in Dermatocosmetics.
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