highly significantp = 4.36 × 10 −11
Using STRINGv11.0 program with the highest confidence interaction score (CIS) of 0.9, processing the 119 genes yielded a protein–protein interaction network of 70 genes, which was found to be highly significant based on hypergeometric test with Benjamini–Hochberg correction ( p = 4.36 × 10 −11 ) ( Figure 2 a).