Furthermore, immune signaling pathways and their components have been presented in the form of a network, where hematopoietic cell lineage appears to be directly controlled by 12 highly significant DEGs; leukocyte transendothelial migration is directly controlled by 10 DEGs; ubiquitin-mediated proteolysis is controlled by 5 DEGs; the insulin signaling pathway is controlled by 6 DEGs; 3 DEGs control platelet activation; 9 DEGs control NK-cell-mediated cytotoxicity; 5 DEGs control TCR and BCR signaling; and 5 DEGs control neurotrophic signaling ( Figure 2B ).
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In-Silico Study of Immune System Associated Genes in Case of Type-2 Diabetes With Insulin Action and Resistance, and/or Obesity.
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