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New Trends in Injection-Based Therapy for Thumb-Base Osteoarthritis: Where Are We and where Are We Going?

Front Pharmacol · 2021 · PMC8079141 · PMID 33927620

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a positive trendno p-value reported
( Heyworth et al., 2008 ) reported no statistically significant differences among the three studied groups, of whom one was treated with two IA injections of hylan, one with a single injection of normal saline (0.9% sodium chloride) followed, after a week, by IA betamethasone, and another one with two IA injections of normal saline; however, a positive trend in hand function, assessed by Disabilities of the Arm, Shoulder, and Hand (DASH) scores, was observed in patients treated with HA.

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