Effect of 2-acetylaminofluorene and its genotoxic metabolites on DNA adduct formation and DNA damage in 3D reconstructed human skin tissue models.

Mutagenesis · 2021 · PMC8081378 · PMID 31816077

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highly significantno p-value reported

In all experiments, treatment of the EpiDermTM skin tissues with MMC as PC resulted in highly significant increases in MN formation after either two or three treatments over 48 h and 72 h, respectively ( Figure 2a–f ).

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