Xiaoyao Pills Ameliorate Depression-like Behaviors and Oxidative Stress Induced by Olfactory Bulbectomy in Rats via the Activation of the PIK3CA-AKT1-NFE2L2/BDNF Signaling Pathway.

Front Pharmacol · 2021 · PMC8082504 · PMID 33935736

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a decreasing trendno p-value reported

As shown in Figures 8A–C , the expression of PIK3CA in the cortex of OB rats was significantly lower than that of the sham rats ( p < 0.05), whereas the expression of AKT1 showed a decreasing trend.

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