Knock out of specific maternal vitellogenins in zebrafish (Danio rerio) evokes vital changes in egg proteomic profiles that resemble the phenotype of poor quality eggs.

BMC Genomics · 2021 · PMC8082894 · PMID 33910518

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vtg -KO caused changes in proteomic profiles of zebrafish eggs In 1-cell stage zebrafish embryos incapacitation of vtg1 , 4 , and 5, or of vtg3, divulged highly significant changes in the proteomic profiles, and thus, in the abundance of proteins involved in energy homeostasis, protein synthesis and cellular proliferation.

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