Staphylococcus aureus ST228 and ST239 as models for expression studies of diverse markers during osteoblast infection and persistence.

At 24 h p.i., ST239‐III bacteria stably persisted intracellularly (45%) and exerted a highly significant cytotoxic activity against osteoblasts, due to the overexpression of hla , as demonstrated by a remarkable decrease in the cellular metabolic status, also confirmed by the expression of the uhp T gene (although not statistically significant).

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