Compared with the empirical results on marginally statistically significant reduction in the risk for death (HR, 0.73; 95% CI, 0.52–1.03) derived from the two-arm RCT of remdesivir, 19 , 20 the point estimate was consistent but our proposed approach was more precise due to the incorporation of information sources derived from both the one-arm study and the two-arm trial.
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Assessing efficacy of antiviral therapy for COVID-19 patients: A case study on remdesivir with bayesian synthesis design and multistate analysis.
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