Estimation of Ontogeny Functions for Renal Transporters Using a Combined Population Pharmacokinetic and Physiology-Based Pharmacokinetic Approach: Application to OAT1,3.

AAPS J · 2021 · PMC8096729 · PMID 33948771

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a small trendno p-value reported

Remarkably, despite a small trend towards under-prediction of CL R values for cefazolin in part of the newborns, all predictions can still be considered accurate.

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