Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson's disease brain.

Mol Neurodegener · 2021 · PMC8097820 · PMID 33947435

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highly significantno p-value reported

H3K27 hyperacetylation in PD is supported by multiple levels of evidence in our study: (a) immunoblot analyses showed a highly significant increase in the acetylated fraction of H3K27 across three brain regions in PD.

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