The incidence, characteristics and outcomes of pregnant women hospitalized with symptomatic and asymptomatic SARS-CoV-2 infection in the UK from March to September 2020: A national cohort study using the UK Obstetric Surveillance System (UKOSS).

Other areas where we feel we have demonstrated appropriate judgement of significance is the inclusion of maternal age in our multivariate model based on our a priori hypothesis, and presentation of other ‘borderline significant’ outcomes, for example the inclusion of hypertension as a risk factor for admission (aOR 3.63, 95% CI 0.99 – 13.30).

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The sentence has been amended by pointing out that numbers are small and the aOR from the sensitivity analysis have been added so that the readers can see the association for hypertension is of borderline significance: Line 222-223: “In the sensitivity analysis, there was some evidence that asthma and hypertension specifically increased the risk of admission, although the numbers in some groups were small (aOR 2.12, 95% CI 1.25-3.58 and aOR 3.63, 95% CI 0.99 – 13.30 respectively, Table S3).” line 255 when noting symptomatic SARS and pregnancy loss less than 24 weeks , if the authors do not wish to add the historical comparison can they explain why that is not used.

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