Access to the relatively large cohort described in this study, followed up in a single centre, has enabled us to show the highly significant hazard ratio (HR = 5.6) for survival when patients are stratified on the basis of a Δ tel above or below −2.4 kb, indicating that patients with mean telomere lengths below this threshold have over a fivefold greater risk of death.
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High-throughput STELA provides a rapid test for the diagnosis of telomere biology disorders.
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