Deficiency of optineurin enhances osteoclast differentiation by attenuating the NRF2-mediated antioxidant response.

Exp Mol Med · 2021 · PMC8102640 · PMID 33864025

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a decreasing trendno p-value reported

However, the Hmox-1 and Gclc levels were significantly lower in the Optn −/− cells than in the Optn +/+ cells, while the Gclm and Nqo1 levels showed a decreasing trend (Fig. 4a ).

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