Content Analysis of 2012-2019 FDA Warning Letters and Notices of Violations using the Economic, Clinical, and Humanistic Outcomes (ECHO) Model.

Innov Pharm · 2021 · PMC8102978 · PMID 34007685

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a positive trendno p-value reported

An average of 2 WLs per year was observed in the study period, which is a positive trend since WLs are more serious ( Table #1 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.