In-hospital prognosis of first-ever noncardiogenic ischemic stroke in patients with and without indication for prestroke antiplatelet therapy: Chinese Stroke Center Alliance.

Among patients without indication, prestroke antiplatelet use was associated with lower mortality (OR 0.73, 95% CI: 0.56–0.96; P=0.0221), but longer hospital stay (OR 1.03, 95% CI: 1–1.07; P=0.0327), and more recurrence of ischemic stroke and TIA (OR 1.59, 95% CI: 1.48–1.70; P<0.0001); while among patients with indication, there was a marginally significant inverse association of prestroke antiplatelet use with NIHSS ≥16 (P<0.0001) and mRS ≥2 (P=0.0003), and prestroke antiplatelet use was not associated with length of hospital stay, recurrence of ischemic stroke and TIA, or mortality.

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