Glyoxalase I disruption and external carbonyl stress impair mitochondrial function in human induced pluripotent stem cells and derived neurons.

Transl Psychiatry · 2021 · PMC8106684 · PMID 33966051

Europe PMC DOI

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0.0640

closest p · 1.3× alpha

0.0640

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The sentences

a decreasing trendP = 0.064so close (0.05 < p ≤ 0.1)

We observed that the fluorescence ratios were similar between the WT and GLO1 KO-hiPSCs under normal conditions, although the ratios for the GLO1 KO-hiPSCs showed a decreasing trend after MGO addition (50 μM, 24 h) compared to those under normal condition ( P = 0.064) or those for MGO-treated WT hiPSCs ( P = 0.068) (Fig. 3A, B ).

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