Barely Significant
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Macrosynteny analysis between Lentinula edodes and Lentinula novae-zelandiae reveals signals of domestication in Lentinula edodes.

Sci Rep · 2021 · PMC8110776 · PMID 33972587

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may be significantno p-value reported
It is reasonable to hypothesize that there may be significant macrosyntenic variation within the L. edodes population, and it is likely these differences would be readily found between wild populations and cultivars that are commercially used.

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