highly significantP < 0.001
Univariate Cox regression showed both GOPM and SHPM to be highly significant in predicting DSS ( P < 0.001, hazard ratio [HR] = 2.92; 95% confidence interval [CI]: 1.91–4.46, Bootstrap P = 0.001 and P < 0.001, HR = 4.92; 95% CI: 3.04–7.97, Bootstrap P = 0.001, respectively).