Analysis of Amount, Size, Protein Phenotype and Molecular Content of Circulating Extracellular Vesicles Identifies New Biomarkers in Multiple Myeloma.

Int J Nanomedicine · 2021 · PMC8114829 · PMID 33994784

Europe PMC DOI

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0.0100

closest p · 0.2× alpha

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boldest claim

The sentences

a decreasing trendp =0.01actually significant

MM patients showed positive linear correlation coefficients for CD38/138+ EVs/mL and CD138EV-MFI and involved sFLCkappa (r=0.74, p =0.02 and r=0.64, p =0.05 respectively; Figure 8A and C ), while the value of CD138+EVs/mL of serum showed a decreasing trend when compared to FLCs (r=−0.8, p =0.01; Figure 8B ).

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a positive trendno p-value reported

Regarding other MM clinical parameters, we observed a positive trend between BM PC percentage and bone lesions, and EV associated biomarkers.

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