failed to achieve significancep = 0.0507
The chi-square test showed U0126 pretreatment tended to reduce the percentage of shrews vomiting (χ 2 (2, 18) = 7.2, p = 0.0302) in response to ZD7288, but failed to achieve significance at the 20 mg/kg dose ( p = 0.0507) ( Figure 9B ).