The biphasic and age-dependent impact of klotho on hallmarks of aging and skeletal muscle function.

Elife · 2021 · PMC8118657 · PMID 33876724

Europe PMC DOI

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a decreasing trendno p-value reported

an increasing trendno p-value reported

Fifteen genes have an increasing trend with aging progression, and 23 genes had a decreasing trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.