Adipokine role in physiopathology of inflammatory and degenerative musculoskeletal diseases.

In these patients, a marginally significant negative correlation between adiponectin serum levels and the body mass index was also observed. 41 Adiponectin and ankylosing spondylitis Ankylosing spondylitis (AS) is a chronic systemic inflammatory disease that primarily affects the axial skeleton (cervical, dorsal, lumbar, and sacroiliac joints), but also peripheral joints (e.g. hip and shoulder), leading to progressive fibrosis and ossification (ankylosis) of the involved structures.

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