Integrative statistical analyses of multiple liquid biopsy analytes in metastatic breast cancer.

Genome Med · 2021 · PMC8130163 · PMID 34001236

Europe PMC DOI

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highly significantno p-value reported

Aggregating the results of hierarchical clustering of individual LBAs into the ELIMA.score resulted in a highly significant correlation with overall survival, thereby bolstering evidence for the additive value of using multiple LBAs.

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borderline significanceno p-value reported

ESR1 ( p =0.05) and BRCA2 ( p =0.05) variants in cfDNA showed borderline significance for a correlation with OS (Fig. 2 e, f).

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