Preferential CEBP binding to T:G mismatches and increased C-to-T human somatic mutations.

Nucleic Acids Res · 2021 · PMC8136768 · PMID 33877329

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probable significanceno p-value reported

This observation has probable significance beyond CEBPβ alone, as other members of the basic leucine-zipper (bZIP) family of TFs would accommodate DNA cytosine methylation within their recognition sequences ( 42 ), and may thus have similar binding preferences for the T:G product of 5mC:G deamination.

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