Epidemiological characteristics of hand, foot, and mouth disease in China: A meta-analysis.

Medicine (Baltimore) · 2021 · PMC8137076 · PMID 34011066

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a decreasing trendno p-value reported

It was highest in 2014 and lowest in 2018, and showed a decreasing trend of incidence during 2014 to 2018.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.