Inulin supplementation ameliorates hyperuricemia and modulates gut microbiota in Uox-knockout mice.

Eur J Nutr · 2021 · PMC8137640 · PMID 33104864

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The increased SCFAs (acetate, propionate and butyrate) were positively related to TJ proteins (ZO-1 and occludin), and negatively correlated with inflammatory cytokines (TNF-α, IL-1β and IL-6), LPS, uremic toxins (IS and PCS) and UA, indicating that SCFAs production may be significant for hyperuricemia relief by inulin treatment (Fig. 8 b).

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