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Viability of preloaded Descemet membrane endothelial keratoplasty grafts with 96-hour shipment.

BMJ Open Ophthalmol · 2021 · PMC8141423 · PMID 34104797

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marginally significantno p-value reported
After 48 hours of shipping, tri-folded DMEK grafts demonstrated a comparable ECL to scrolled DMEK grafts, with a marginally significant trend demonstrating 4.3% less ECL in tri-folded as compared with scrolled grafts. 4 5 However, there has been limited investigation into the effect of extended shipping on DMEK grafts with a comparison between these two methods. 6 In 2019, over 28 000 corneas were exported internationally from the USA for keratoplasty. 7 The ease of said international transplants would be greatly improved if grafts could be preloaded and were to remain viable during prolonged shipping.

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