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Tolerability and age-dependent toxicokinetics following perinatal hydroxyurea treatment in Sprague Dawley rats.

J Appl Toxicol · 2021 · PMC8144245 · PMID 33241551

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a decreasing trendno p-value reported
There was a decreasing trend in body weight with increasing dose starting on PND 13 and body weight was significantly lower than control in the 75, 100, and 150 mg/kg/day groups starting on PND 16 (Figure 2 ).

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