extremely significantp < 0.001
The down-regulation of miR-664b has a potential association with the extremely significant up-regulation of interleukin 17A ( IL17A ) (18.584-fold change, p < 0.001) in S. aureus -inoculated quarters, which plays a crucial role in the defense of Gram-positive bacterial infection and inflammation development [ 45 , 46 , 47 ].