Combining Visible Light and Non-Focused Ultrasound Significantly Reduces <i>Propionibacterium acnes</i> Biofilm While Having Limited Effect on Host Cells.

The percent of Alamar blue reduction in cells exposed to light plus ultrasound at Day 0 was not different from that of the mock cells ( p > 0.05), and slightly lower than the mock cells at Day 1, although this was only of borderline significance ( p = 0.05, ANOVA for differences of the mean).

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There was a slight trend toward fewer cells with increasing light exposure at Day 1, but these values were no different than the range of values found among the mock samples, and the trend was not significant ( p = 0.78, ANOVA for difference of the means).

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