Consistently, a correlation of SEC62 amplification with overall survival in 40,006 cancer patients (45 different tumor entities) based on publicly available DNA sequencing and clinical data (cBio Portal for cancer genomics; https://www.cbioportal.org , accessed on 21 April 2021) shows a highly significant association of SEC62 amplifications with poor prognosis ( Figure 10 b).
← all excerpts
Complexity and Specificity of Sec61-Channelopathies: Human Diseases Affecting Gating of the Sec61 Complex.
1
—
—