Anti-SARS-CoV-2 Receptor-Binding Domain Total Antibodies Response in Seropositive and Seronegative Healthcare Workers Undergoing COVID-19 mRNA BNT162b2 Vaccination.

A highly significant correlation could be found between the ratios of increase from the individual baseline antibodies level observed after the first (21 days) and second (50 days) vaccine doses in both baseline seronegative ( r = 0.68; 0.63 to 0.71; p < 0.001) and baseline seropositive ( r = 0.95; 95% CI, 0.94 to 0.96; p < 0.001) recipients.

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