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Changing epidemiology of calcific aortic valve disease: 30-year trends of incidence, prevalence, and deaths across 204 countries and territories.

Aging (Albany NY) · 2021 · PMC8148466 · PMID 33973531

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an increasing trendno p-value reported
In contrast, the ASR indicated an increasing trend if the EAPC estimate and lower boundary of its 95% CI were both >0.

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a decreasing trendno p-value reported
Since 1990, no SDI or GBD regions have shown a decreasing trend in CAVD deaths or ASDR ( Table 1 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.