A Japanese hereditary spastic paraplegia family with a rare nonsynonymous variant in the SPAST gene.

Hum Genome Var · 2021 · PMC8149642 · PMID 34035234

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marginally significantno p-value reported

A high CADD score that was marginally significant (CADD = 34) was also observed for the variant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.