Modified Gold Nanoparticles for Efficient Delivery of Betulinic Acid to Cancer Cell Mitochondria.

Int J Mol Sci · 2021 · PMC8150271 · PMID 34064888

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highly significantno p-value reported

The assessment of the impact of free BA, and the nanocomplexes on mitochondrial membrane potential revealed highly significant membrane depolarizations by T-Au-PEG-BA and T-Au[PLL-g-PEG]-BA compared to the untargeted (Au-PEG-BA and Au-[PLL-g-PEG]-BA), and free BA, highlighting the efficacy of this targeted approach.

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