Ubiquinone Metabolism and Transcription HIF-1 Targets Pathway Are Toxicity Signature Pathways Present in Extracellular Vesicles of Paraquat-Exposed Human Brain Microvascular Endothelial Cells.

Int J Mol Sci · 2021 · PMC8150401 · PMID 34064677

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highly significantno p-value reported

The major finding of this study is that EVs exposed for 24 h to paraquat at 100 μM displayed modulation of two biological pathways, which are highly significant: the ubiquinone metabolism and the transcription of HIF-1 targets.

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