Gene Expression Levels of the Prolyl Hydroxylase Domain Proteins PHD1 and PHD2 but Not PHD3 Are Decreased in Primary Tumours and Correlate with Poor Prognosis of Patients with Surgically Resected Non-Small-Cell Lung Cancer.

Cancers (Basel) · 2021 · PMC8150639 · PMID 34065840

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0890

boldest claim

The sentences

borderline significancep = 0.06so close (0.05 < p ≤ 0.1)

Multivariate Cox proportional hazards regression analysis adjusting for PS, pTNM stage, tumour size and nodular involvement revealed that lower PHD1 mRNA expression in the primary tumour had borderline significance for shorter OS (HR = 0.908; 95% CI: 0.822–1.004; p = 0.06) ( Table 4 ). 4.

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a possible trendp = 0.0890so close (0.05 < p ≤ 0.1)

A possible trend towards a lower expression of PHD2 in stage II + III vs. stage I disease was observed ( p = 0.0890).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Gene Expression Levels of the Prolyl Hydroxylase Domain Proteins <i>PHD1</i> and <i>PHD2</i> but Not <i>PHD3</i> Are Decreased in Primary Tumours and Correlate with Poor Prognosis of Patients with Surgically Resected Non-Small-Cell Lung Cancer.

The sentences