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Peripheral blood basophils are the main source for early interleukin-4 secretion upon in vitro stimulation with Culicoides allergen in allergic horses.

PLoS One · 2021 · PMC8153460 · PMID 34038479

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an overall trendno p-value reported
Here, we reported that allergic horses have an overall trend towards higher IL-4 production in their PBMC after stimulation with Cul extract in comparison to non-allergic horses.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.