Reduced adaptation of glutamatergic stress response is associated with pessimistic expectations in depression.

Nat Commun · 2021 · PMC8155144 · PMID 34039978

Europe PMC DOI

hedged sentences

0.0630

closest p · 1.3× alpha

0.0630

boldest claim

The sentences

marginally significantp = 0.063so close (0.05 < p ≤ 0.1)

We observed a marginally significant effect of Timepoint ( F (1.62,129.94) = 3.03, p = 0.063), marginally significant main effect of Group ( F (2,80) = 2.86, p = 0.063), and significant Timepoint × Group interaction ( F (3.25,129.94) = 3.19, p = 0.023).

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highly significantno p-value reported

Main effects of Group were highly significant for all three questions ( ps < 1.0 × 10 −13 ), driven by lower ratings of the NSC group.

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