Reviewing Evidence for the Relationship of EEG Abnormalities and RTT Phenotype Paralleled by Insights from Animal Studies.

Int J Mol Sci · 2021 · PMC8157853 · PMID 34069993

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Ammanuel and colleagues found that in patients with RTT ( n = 10) the power of 35–45 Hz oscillations during slow wave sleep (SWS) did not follow a typical and highly significant decrease from 2–5 to 6–9 years of age, suggesting that subjects with RTT do not exhibit a normal developmental reduction in cortical excitability [ 141 ].

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