Effect of Vitamin K-Mediated PXR Activation on Drug-Metabolizing Gene Expression in Human Intestinal Carcinoma LS180 Cell Line.

Nutrients · 2021 · PMC8157877 · PMID 34069974

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an increasing trendno p-value reported

Similarly, CYP3A4 mRNA expression was significantly increased by MK-4 treatment when compared with that of the control, and an increasing trend was observed when treated with VK 1 and MK-7 ( Figure 4 b).

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