As shown in Figure 8 , TTHX1114 treatment had an overall trend in reduced production of pro-inflammatory cytokines (i.e., IL1α, IL-2, IL-12, IL-15, IL17-α, TNF-α, CCL-5) and chemokines (i.e., CXCL10) produced by the monocytes-derived pro-inflammatory M1 macrophages.
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Healing of Ocular Herpetic Disease Following Treatment With an Engineered FGF-1 Is Associated With Increased Corneal Anti-Inflammatory M2 Macrophages.
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