Association between oral contraceptive use and pancreatic cancer risk: A systematic review and meta-analysis.

World J Gastroenterol · 2021 · PMC8160625 · PMID 34092981

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borderline significantno p-value reported

Pooled risk estimates from case-control studies were not statistically significant (RR = 0.85, 95%CI: 0.64-1.14), while the association between ever use of OC and decreased risk of pancreatic cancer was borderline significant in cohort studies (RR = 0.84, 95%CI: 0.70-1.00).

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marginally significantno p-value reported

Subsequently, the authors noted that their subgroup analyses by study design showed a marginally significant increased risk of pancreatic cancer associated with OC use in cohort studies (RR = 1.09, 95%CI: 1.00-1.29).

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