Current EU regulatory requirements for the assessment of chemicals and cosmetic products: challenges and opportunities for introducing new approach methodologies.

Arch Toxicol · 2021 · PMC8166712 · PMID 33851225

Europe PMC DOI

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an increasing trendno p-value reported

While in recent years an increasing trend in the use of alternative methods for skin sensitisation has been observed, in areas such as skin irritation/corrosion, serious eye damage/eye irritation and pyrogenicity testing, concerns still exist with regards to animal uses, as highlighted in the most recent European statistics (EC 2020a ).

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