Two phase III trials (FFCD trial 9002 and the ENG trial) both showed a nonsignificant trend for improvement in DFS and OS for patients treated with adjuvant chemotherapy 22 , 23 , but both trials close prematurely because of slow accrual.
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Dynamic monitoring of circulating tumor DNA to predict prognosis and efficacy of adjuvant chemotherapy after resection of colorectal liver metastases.
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