The evolving proteome of SARS-CoV-2 predominantly uses mutation combination strategy for survival.

Comput Struct Biotechnol J · 2021 · PMC8178965 · PMID 34109017

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highly significantno p-value reported

Emergence of highly significant trio mutations (N protein:A220V, ORF10protein:V30L and Spike:A222V) in Europe and their merging with Spike:D614G and Nsp12:P323L (clade-3b) has led to a new subclade 3f.

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