Barely Significant
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Defining and navigating macrocycle chemical space.

Chem Sci · 2021 · PMC8179434 · PMID 34163695

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a notable trendno p-value reported
44,45,49,52 A notable trend in Fig. 3A is that the MC drugs that are largely synthetic in origin occupy a different area in MC property compared to those that are natural products or their close derivatives.

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