Barely Significant
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Melatonin alleviates titanium nanoparticles induced osteolysis via activation of butyrate/GPR109A signaling pathway.

J Nanobiotechnology · 2021 · PMC8182936 · PMID 34092246

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an increasing trendno p-value reported
More importantly, there was still an increasing trend in the genera of SCFAs-producing bacteria, such as Bifidobacterium, Bacteroides, Clostridium, Eubacterium, Ruminococcus (Fig. 3 B).

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